Noggin has been shown to be a high-affinity binding protein to BMP and antagonizes BMP bio-activities. It can be added to cell culture medium for embryonic stem cells to maintain pluripotency.
The recombinant human Noggin comprises 216 amino acids after removal of the signal peptide and has a predicted molecular mass of 24.6 kDa. As a result of glycosylation, it migrates as an approximately 30 kDa band in SDS-PAGE under reducing conditions StemRD's Noggin is made in human 293 cells, which renders human-specific post-translational modifications. We purified this product through a series of chromatography.
StemRD Inc. is located in the San Francisco Bay Area, we specialize in producing premier research reagents for the stem cell research community. Our mission is to empower stem cell R&D through innovative technologies. Our proprietary technology in protein expression and purification has allowed efficient production of several important factors, such as WNT, Hedgehog, TGF-ß family members and Differentiation Kits, that are difficult to obtain by conventional methods.
StemRD 是美国一家聚焦于尖端干细胞研究的公司,拥有蛋白表达和纯化方面的专利技术。拥有被美国FDA认证的可用于GMP生产治疗型多肽的设施。StemRD的实验室拥有包括组织培养、细胞处理、超离心、超过滤、FPLC、HPLC和LC/MS等一系列先进设备。其中干细胞研究用生长/分化因子、小分子化合物均包括目前研究较多的WNT/β-catenin、TGF-β、Hedgehog、Notch等信号通路等。
Uante,您的科研物资战略合作伙伴!
重庆市寰宇安泰生物科技有限公司
固定电话:023-67946738
全国热线:400-8623-068