WNT-3a is a member of the WNT family of signaling proteins that play key roles in embryonic development and the maintenance of adult tissues. WNT-3a is a prototypic canonical WNT that signals through the b-catenin pathway. The predicted size of human WNT-3a is a monomeric protein containing 328 amino acid residues. Due to glycosylation, it migrates at an apparent molecular weight of 38 - 41 kDa on SDS-PAGE under non-reducing conditions. StemRD’s WNT-3a is produced from a human cell line overexpressing human Wnt-3a cDNA in protein-free medium. Purification is done by a proprietary process that is distinct from the published method.
StemRD Inc. is located in the San Francisco Bay Area, we specialize in producing premier research reagents for the stem cell research community. Our mission is to empower stem cell R&D through innovative technologies. Our proprietary technology in protein expression and purification has allowed efficient production of several important factors, such as WNT, Hedgehog, TGF-ß family members and Differentiation Kits, that are difficult to obtain by conventional methods.
StemRD 是美国一家聚焦于尖端干细胞研究的公司,拥有蛋白表达和纯化方面的专利技术。拥有被美国FDA认证的可用于GMP生产治疗型多肽的设施。StemRD的实验室拥有包括组织培养、细胞处理、超离心、超过滤、FPLC、HPLC和LC/MS等一系列先进设备。其中干细胞研究用生长/分化因子、小分子化合物均包括目前研究较多的WNT/β-catenin、TGF-β、Hedgehog、Notch等信号通路等。
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重庆市寰宇安泰生物科技有限公司
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