Anti-Human CD2 Antibody, Clone RPA-2.10
Product Overview
The RPA-2.10 antibody reacts with CD2, an ~50 kDa type I transmembrane glycoprotein and a member of the immunoglobulin (Ig) superfamily; two Ig-like domains are located in its extracellular portion. CD2 is broadly expressed on peripheral T and NK cells, dendritic cells, erythrocytes, most thymic T cells, subsets of thymic B cells, and on the endothelium. CD2 expression appears early during T cell differentiation. Aberrant expression has been observed in some lymphomas and myeloid leukemias. CD2 is critically important for T cell activation and signaling, and lymphocyte adhesion. The primary ligand for CD2 is CD58 (LFA-3) located on antigen-presenting cells, with additional ligands comprising CD15 (SSEA-1), CD48 and CD59. Notably, the RPA-2.10 antibody blocks the mixed lymphocyte reaction.
This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ HLA CD3 Positive Selection Kit (Catalog #18051HLA), EasySep™ Human CD3 Positive Selection Kit (Catalog #18051), EasySep™ HLA Whole Blood CD3 Positive Selection Kit (Catalog #18081HLA) and EasySep™ Human Whole Blood CD3 Positive Selection Kit (Catalog #18081).
Subtype:一抗
Target Antigen:CD2
Reactive Species:狒狒; 卷尾猴; 黑猩猩; 食蟹猴; 人; 恒河猴; 猪; 猕猴; 松鼠猴
Conjugation:APC; 生物素; FITC; PE; 未结合
Host Species:小鼠
Cell Type:T细胞
Application:细胞分离; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; Western印迹法
Area of Interest:免疫学
Clone:RPA-2.10
Gene ID:914
Isotype:IgG1, kappa
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Anti-Hu CD2, RPA-2.10, PE, 25 | 60007PE.1 | 25 tests |
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Anti-Hu CD2, RPA-2.10, BT, 100µg | 60007BT | 100 µg |
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Anti-Hu CD2, RPA-2.10 | 60007 | 100 µg |
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