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Anti-Human CD5 Antibody, Clone UCHT2
Product Overview
The UCHT2 antibody reacts with CD5, an ~67 kDa single-chain type I glycoprotein and member of the scavenger receptor superfamily, which is constitutively expressed on thymocytes, T cells, B cell subsets, peripheral blood dendritic cells and some leukemia and lymphoma cells, including chronic B lymphocytic leukemia (B-CLL) cells. CD5 is expressed at low levels on thymocytes and at high density on mature T cells. Putative ligands include CD5L and CD72. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T cell/B cell interactions via its physical and functional associations with the T cell receptor/CD3 complex and the B-cell receptor. Studies with CD5 knockout mice indicate that CD5 negatively regulates antigen receptor-mediated signaling in thymocytes and mature T cells. The UCHT2 antibody binds to epitope 2 located in the extracellular domain of CD5.
Subtype:一抗
Target Antigen:CD5
Reactive Species:卷尾猴; 黑猩猩; 普通狨猴; 食蟹猴; 人; 枭猴; 猕猴
Conjugation:APC; 生物素; FITC; PE; PerCP-Cyanine5.5; 未结合
Host Species:小鼠
Cell Type:T细胞
Application:流式细胞术; 免疫细胞化学; 免疫组化; Western印迹法
Area of Interest:免疫学; 干细胞生物学
Clone:UCHT2
Gene ID:921
Isotype:IgG1, kappa
Related products
Description | Catalog # | Format |
Anti-Hu CD5, UCHT2, UC, 100µg | 60082 | 100 µg |
Anti-Hu CD5, UCHT2, PS, 100tests | 60082PS | 100 tests |
Anti-Hu CD5, UCHT2, PS, 25tests | 60082PS.1 | 25 tests |
Anti-Hu CD5, UCHT2, PE, 100tests | 60082PE | 100 tests |
Anti-Hu CD5, UCHT2, PE, 25tests | 60082PE.1 | 25 tests |
Anti-Hu CD5, UCHT2, FI, 100tests | 60082FI | 100 tests |
Anti-Hu CD5, UCHT2, FI, 25tests | 60082FI.1 | 25 tests |
Anti-Hu CD5, UCHT2, BT, 100µg | 60082BT | 100 µg |
Anti-Hu CD5, UCHT2, AZ, 100tests | 60082AZ | 100 tests |
Anti-Hu CD5, UCHT2, AZ, 25tests | 60082AZ.1 | 25 tests |
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