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Stemcell  60084FI  Anti-Human CD36 Antibody, Clone FA6-152

Product Overview

The FA6-152 antibody reacts with CD36, an ~88 kDa transmembrane glycoprotein that functions as a scavenger receptor, cell adhesion molecule and signal transducer on the surface of many types of cells including platelets, monocytes, macrophages, erythrocyte precursors, endothelial and epithelial cells, and some macrophage-derived dendritic cells. The topology of the protein is thought to comprise a large extracellular loop with the N- and C-termini both inserted through the cell membrane. CD36 binds multiple ligands such as thrombospondin, collagen, lipoproteins and long-chain fatty acids, and has evident roles in the phagocytotic clearance of apoptotic cells, inhibition of angiogenesis, metabolism of glucose and fatty acids, inflammation, and the pathogenesis of malaria. Binding of the FA6-152 antibody to CD36 reportedly blocks its interaction with thrombospondin, collagen, apoptotic cells and modified LDL, and induces agglutination of fetal but not adult erythrocytes.

Subtype:一抗

Target Antigen:CD36

Reactive Species:人; 大鼠

Conjugation:FITC; 未结合

Host Species:小鼠

Cell Type:单核细胞; 其他

Application:细胞分离; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀; 中和及阻滞; Western印迹法

Area of Interest:免疫学

Clone:FA6-152

Gene ID:948

Isotype:IgG1, kappa

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