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Stemcell 60086FI Anti-Human CD66b Antibody, Clone G10F5
Product Overview
The G10F5 antibody reacts with CD66b (previously denoted CD67), an ~95 kDa single-chain glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed by neutrophilic and eosinophilic granulocytes. CD66b is a member of the carcinoembryonic antigen (CEA)-like subfamily of proteins within the immunoglobulin superfamily and possesses two Ig-like C2-type domains and one Ig-like V-type domain. In neutrophils, CD66b is localized within granules in the cytoplasm as well as being expressed on the plasma membrane. Surface expression levels increase upon granulocyte activation, an effect induced by stimulators such as phorbol myristate acetate (PMA), calcium ionophore and N-formylmethionyl-leucyl-phenylalanine (FMLP). CD66b appears to play a role as a signaling receptor involved in cell adhesion, phagocytosis and chemotaxis by regulating granulocyte activation and adhesion to several proteins, including CD66c, galectin-3, fibronectin and E-selectin.
Subtype:一抗
Target Antigen:CD66b
Reactive Species:黑猩猩; 人
Conjugation:APC; FITC; PE; 未结合
Host Species:小鼠
Cell Type:粒细胞及其亚型; 髓系细胞
Application:流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀; Western印迹法
Area of Interest:免疫学
Clone:G10F5
Gene ID:1088
Isotype:IgM, kappa
Related products
Description | Catalog # | Format |
Anti-Hu CD66b, G10F5, UC, 100µg | 60086 | 100 µg |
Anti-Hu CD66b, G10F5, PE, 100tests | 60086PE | 100 tests |
Anti-Hu CD66b, G10F5, PE, 25tests | 60086PE.1 | 25 tests |
Anti-Hu CD66b, G10F5, FI, 100tests | 60086FI | 100 tests |
Anti-Hu CD66b, G10F5, FI, 25tests | 60086FI.1 | 25 tests |
Anti-Hu CD66b, G10F5, AZ, 100tests | 60086AZ | 100 tests |
Anti-Hu CD66b, G10F5, AZ, 25tests | 60086AZ.1 | 25 tests |
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