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Stemcell 60110BT Anti-Human CD123 (IL-3Rα) Antibody, Clone 6H6
Product Overview
The 6H6 antibody reacts with human CD123 (IL-3 receptor subunit α), an ~70 kDa type I transmembrane glycoprotein belonging to the type I cytokine receptor family (type 5 subfamily) and the Ig superfamily. CD123 constitutes the ligand-binding α chain of the heterodimeric IL-3 receptor. CD123 binds IL-3 with low affinity per se, but when associated with CD131, the signal-transducing β chain of the receptor, high affinity binding of IL-3 is observed. CD123 is expressed by hematopoietic progenitor cells, endothelial cells, basophils, eosinophils, mast cells, monocytes, macrophages, dendritic cells, megakaryocytes, a subset of B cells, and by neutrophils if cultured in the presence of GM-CSF. IL-3 binding to CD123 stimulates proliferation, differentiation and viability of hematopoietic cells. CD123 is highly expressed in malignancies such as acute leukemia. The 6H6 antibody does not inhibit binding of IL-3 to either CD123 or the IL-3 receptor.
Subtype:一抗
Target Antigen:CD123 (IL-3Rα)
Reactive Species:人; 猕猴; 白颈白眉猴
Conjugation:APC; 生物素; FITC; PE; PerCP-Cyanine5.5; 未结合
Host Species:小鼠
Cell Type:树突状细胞; 粒细胞及其亚型; 造血干细胞和祖细胞; 髓系细胞
Application:CyTOF; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀; Western印迹法
Area of Interest:免疫学
Clone:6H6
Gene ID:3563
Isotype:IgG1, kappa
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Anti-Hu CD123, 6H6, UC, 100µg | 60110 | 100 µg |
Anti-Hu CD123, 6H6, UC, 25µg | 60110.1 | 25 µg |
Anti-Hu CD123, 6H6, PE, 100tests | 60110PE | 100 tests |
Anti-Hu CD123, 6H6, PE, 25tests | 60110PE.1 | 25 tests |
Anti-Hu CD123, 6H6, FI, 100tests | 60110FI | 100 tests |
Anti-Hu CD123, 6H6, FI, 25tests | 60110FI.1 | 25 tests |
Anti-Hu CD123, 6H6, BT, 100µg | 60110BT | 100 µg |
Anti-Hu CD123, 6H6, BT, 25µg | 60110BT.1 | 25 µg |
Anti-Hu CD123, 6H6, AZ, 100tests | 60110AZ | 100 tests |
Anti-Hu CD123, 6H6, AZ, 25tests | 60110AZ.1 | 25 tests |
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