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Stemcell 60090AZ.1 Anti-Human CD196 (CCR6) Antibody, Clone G034E3
Product Overview
The G034E3 antibody reacts with an extracellular epitope on human CD196 (CCR6). CD196 is an ~42 kDa seven-pass G protein-coupled transmembrane chemokine receptor expressed predominantly on the surface of immature dendritic, B, and memory T cells, but also on natural killer and Langerhans cells. The chemokine CCL20 (MIP-3α) has been identified as a ligand for CD196 and its binding induces an increase in the intracellular Ca++ ion concentration. CD196 may play roles in B cell maturation and the differentiation of B and T cells, and appears to be involved in chemotactic recruitment of CD196-expressing cells during the immune and inflammatory responses, a function implicated in the pathogenesis of diseases such as rheumatoid arthritis, inflammatory bowel disease and psoriasis. Abundant expression of CD196 is also observed on B cells of patients with progressive chronic lymphocytic leukemia.
Subtype:一抗
Target Antigen:CD196 (CCR6)
Reactive Species:食蟹猴; 人; 猕猴
Conjugation:Alexa Fluor 488; APC; FITC; PE; 未结合
Host Species:小鼠
Cell Type:T细胞; T细胞，其他亚型
Application:流式细胞术
Area of Interest:免疫学
Clone:G034E3
Gene ID:1235
Isotype:IgG2b, kappa
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Description | Catalog # | Format |
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Anti-Hu CD196 (CCR6), G034E3, FI, 100t | 60090FI | 100 tests |
Anti-Hu CD196 (CCR6), G034E3, FI, 25t | 60090FI.1 | 25 tests |
Anti-Hu CD196 (CCR6), G034E3, AZ, 100t | 60090AZ | 100 tests |
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Anti-Hu CD196 (CCR6), G034E3, AD, 25t | 60090AD.1 | 25 tests |
Anti-Hu CD196 (CCR6), G034E3, 500ug | 60090 | 500 µg |
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