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Stemcell 60067 Anti-Human TRA-2-54 Antibody, Clone TRA-2-54/2J
Product Overview
The TRA-2-54/2J antibody reacts with the tissue non-specific isoform of alkaline phosphatase (AP), which is expressed at high levels in undifferentiated pluripotent stem cells such as human and mouse embryonic stem (ES) cells, as well as induced pluripotent stem (iPS) and embryonal carcinoma (EC) cells. This isozyme of AP is the same as that expressed by liver, bone and kidney cells. Levels of AP decrease upon differentiation and, thus, the TRA-2-54/2J antibody can be used to monitor the differentiation status of pluripotent stem cells. The TRA-2-54/2J antibody does not cross-react with other isozymes of AP, which differ through post-translational modification, and reportedly does not recognize AP from cow, dog, goat, Guinea pig, hamster, mouse, rat or sheep, or Old World Monkeys such as the rhesus monkey, baboon and African green monkey.
Subtype:一抗
Target Antigen:TRA-2-54
Reactive Species:猫; 黑猩猩; 人; 非人灵长类动物; 猪; 兔
Conjugation:未结合
Host Species:小鼠
Cell Type:多能干细胞
Application:流式细胞术; 免疫细胞化学; 免疫荧光; 免疫组化; Western印迹法
Area of Interest:干细胞生物学
Clone:TRA-2-54/2J
Gene ID:249
Isotype:IgG1, kappa
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