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Stemcell 60017BT Anti-Mouse CD4 Antibody, Clone RM4-5
Product Overview
The RM4-5 antibody reacts with mouse CD4, an ~55 kDa single-chain type 1 transmembrane glycoprotein and member of the immunoglobin (Ig) superfamily; CD4 contains four extracellular Ig-like domains. CD4 is expressed at relatively high levels by most thymocytes and a subpopulation of T cells (T-helper/inducer cells), and at lower levels on dendritic cells. In the mouse, CD4 is not expressed by monocytes/macrophages. CD4 binds to a non-polymorphic region of MHC II and acts as a co-receptor to the T cell receptor (TCR) in MHC II-restricted antigen recognition by enhancing the avidity of the association between the TCR and MHC II-antigen complex. CD4 also functions to amplify signals from the TCR to the cytoplasm through the interaction of its intracellular domain with cytoplasmic tyrosine kinases such as Lck. Binding of the RM4-5 antibody to CD4 inhibits ligand binding in vitro. Moreover, binding of the RM4-5 antibody can be blocked by the clone GK1.5 antibody.
This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD4+ T Cell Enrichment Kit (Catalog #19752) and EasySep™ Mouse CD4+ T Cell Isolation Kit (Catalog #19852).
Subtype:一抗
Target Antigen:CD4
Reactive Species:小鼠
Conjugation:Alexa Fluor 488; APC; 生物素; FITC; PE; PerCP-Cyanine5.5; 未结合
Host Species:大鼠
Cell Type:T细胞; CD4+T细胞; 调节性T细胞
Application:细胞分离; CyTOF; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀; Western印迹法
Area of Interest:免疫学
Clone:RM4-5
Gene ID:12504
Isotype:IgG2a, kappa
Related products
Description | Catalog # | Format |
Anti-Ms CD4, RM4-5, PS, 100µg | 60017PS | 100 µg |
Anti-Ms CD4, RM4-5, PS, 25µg | 60017PS.1 | 25 µg |
Anti-Ms CD4, RM4-5, FI, 500µg | 60017FI | 500 µg |
Anti-Ms CD4, RM4-5, FI, 50µg | 60017FI.1 | 50 µg |
Anti-Ms CD4, RM4-5, BT, 500µg | 60017BT | 500 µg |
Anti-Ms CD4, RM4-5, BT, 50µg | 60017BT.1 | 50 µg |
Anti-Ms CD4, RM4-5, AZ, 100µg | 60017AZ | 100 µg |
Anti-Ms CD4, RM4-5, AZ, 25µg | 60017AZ.1 | 25 µg |
Anti-Ms CD4, RM4-5, AD, 25 | 60017AD.1 | 25 µg |
Anti-Ms CD4, RM4-5, AD | 60017AD | 100 µg |
Anti-Ms CD4, RM4-5 | 60017 | 500 µg |
Anti-Ms CD4, RM4-4, UC, 100µg | 60029.1 | 100 µg |
Anti-Ms CD4, RM4-4, UC, 50µg | 60029.2 | 50 µg |
Anti-Ms CD4, RM4-4, UC, 1mg | 60029 | 1 mg |
Anti-Ms CD4, RM4-4, PE, 200µg | 60029PE | 200 µg |
Anti-Ms CD4, RM4-4, PE, 50µg | 60029PE.1 | 50 µg |
Anti-Ms CD4, RM4-4, FI, 500µg | 60029FI | 500 µg |
Anti-Ms CD4, RM4-4, FI, 50µg | 60029FI.1 | 50 µg |
Anti-Ms CD4, RM4-4, BT, 500µg | 60029BT | 500 µg |
Anti-Ms CD4, RM4-4, BT, 100µg | 60029BT.1 | 100 µg |
Anti-Ms CD4, RM4-4, BT, 50µg | 60029BT.2 | 50 µg |
Anti-Ms CD4, RM4-4, AZ, 100µg | 60029AZ | 100 µg |
Anti-Ms CD4, RM4-4, AZ, 25µg | 60029AZ.1 | 25 µg |
Anti-Ms CD4 , RM4-5, PE, 50 | 60017PE.1 | 50 µg |
Anti-Ms CD4 , RM4-5, PE | 60017PE | 200 µg |
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