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Stemcell 60001FI Anti-Mouse CD11b Antibody, Clone M1/70
Product Overview
The M1/70 antibody reacts with CD11b, an ~170 kDa type 1 transmembrane glycoprotein which associates non-covalently with CD18 to form the heterodimeric Mac-1 receptor. Through its interactions with ligands such as ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen, Mac-1 functions in several processes, including the adherence of neutrophils and monocytes to stimulated endothelium and phagocytosis of complement-coated particles. CD11b is expressed on the surface of granulocytes, monocytes, NK cells, dendritic cells, tissue macrophages and subsets of T and B cells, and has been used as a marker to distinguish naïve and memory CD8+ T cells. CD11b is a relatively late marker for myeloid differentiation and is undetectable on most myelomonocytic hematopoietic progenitor cells and more primitive cells. The M1/70 antibody reportedly blocks iC3b binding to Mac-1.
This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse Monocyte Enrichment Kit (Catalog #19761).
Subtype:一抗
Target Antigen:CD11b
Reactive Species:狒狒; 黑猩猩; 食蟹猴; 人; 小鼠; 兔; 猕猴
Conjugation:Alexa Fluor 488; APC; 生物素; FITC; PE; PerCP-Cyanine5.5; 未结合
Host Species:大鼠
Cell Type:粒细胞及其亚型; 单核细胞
Application:细胞分离; CyTOF; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀
Area of Interest:免疫学
Clone:M1/70
Gene ID:16409
Isotype:IgG2b, kappa
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Anti-Ms CD11c, N418, PE, 50 | 60002PE.1 | 50 µg |
Anti-Ms CD11c, N418, PE | 60002PE | 200 µg |
Anti-Ms CD11c, N418, FI, 500µg | 60002FI | 500 µg |
Anti-Ms CD11c, N418, FI, 50µg | 60002FI.1 | 50 µg |
Anti-Ms CD11c, N418, BT, 500µg | 60002BT | 500 µg |
Anti-Ms CD11c, N418, BT, 50µg | 60002BT.1 | 50 µg |
Anti-Ms CD11c, N418, AZ, 100µg | 60002AZ | 100 µg |
Anti-Ms CD11c, N418, AZ, 25µg | 60002AZ.1 | 25 µg |
Anti-Ms CD11c, N418, AD, 25 | 60002AD.1 | 25 µg |
Anti-Ms CD11c, N418, AD | 60002AD | 100 µg |
Anti-Ms CD11c, N418 | 60002 | 500 µg |
Anti-Ms CD11b, M1/70, PS, 100µg | 60001PS | 100 µg |
Anti-Ms CD11b, M1/70, PS, 25µg | 60001PS.1 | 25 µg |
Anti-Ms CD11b, M1/70, PE, 50 | 60001PE.1 | 50 µg |
Anti-Ms CD11b, M1/70, PE | 60001PE | 200 µg |
Anti-Ms CD11b, M1/70, FI, 500µg | 60001FI | 500 µg |
Anti-Ms CD11b, M1/70, FI, 50µg | 60001FI.1 | 50 µg |
Anti-Ms CD11b, M1/70, BT, 500µg | 60001BT | 500 µg |
Anti-Ms CD11b, M1/70, BT, 50µg | 60001BT.1 | 50 µg |
Anti-Ms CD11b, M1/70, AZ, 100µg | 60001AZ | 100 µg |
Anti-Ms CD11b, M1/70, AZ, 25µg | 60001AZ.1 | 25 µg |
Anti-Ms CD11b, M1/70, AD, 25 | 60001AD.1 | 25 µg |
Anti-Ms CD11b, M1/70, AD | 60001AD | 100 µg |
Anti-Ms CD11b, M1/70 | 60001 | 500 µg |
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