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Stemcell 60068AZ.1 Anti-Mouse CD44 Antibody, Clone IM7
Product Overview
The IM7 antibody reacts with CD44 (Ly-24), an ~80 - 95 kDa type 1 transmembrane glycoprotein involved in cell-cell and cell-matrix interactions. CD44 is expressed on the surface of many cells, including leukocytes, hepatocytes, endothelial, epithelial, and mesenchymal cells. Expression levels increase upon activation of T and B cells, and memory cells exhibit a CD44[High] phenotype. CD44 binds many ligands, including hyaluronic acid, collagen, fibronectin, growth factors and metalloproteinases, thus modulating processes such as lymphocyte activation, recirculation and homing, leukocyte rolling and aggregation, hematopoiesis, and tumor metastasis. Numerous disorders are associated with altered expression or dysfunction of CD44. Many CD44 isoforms have been identified, with alternative splicing, differential N- and O- glycosylation, and sulfation mediating the functional role(s) played by the protein in a specific cell. The IM7 monoclonal antibody reacts with an extracellular epitope found on all isoforms of CD44 and both murine allotypes.
This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse CD4+ T Cell Enrichment Kit (Catalog #19752).
Subtype:一抗
Target Antigen:CD44
Reactive Species:狒狒; 猫; 黑猩猩; 牛; 食蟹猴; 狗; 马; 人; 小鼠; 猪; 猕猴; 松鼠猴
Conjugation:Alexa Fluor 488; APC; 生物素; FITC; PE; PerCP-Cyanine5.5; 未结合
Host Species:大鼠
Cell Type:乳腺细胞; T细胞
Application:细胞分离; CyTOF; ELISA; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀
Area of Interest:上皮细胞生物学; 免疫学; 干细胞生物学
Clone:IM7
Gene ID:12505/960
Isotype:IgG2b, kappa
Related products
Description | Catalog # | Format |
Anti-Ms CD44, IM7, PS, 100µg | 60068PS | 100 µg |
Anti-Ms CD44, IM7, PS, 25µg | 60068PS.1 | 25 µg |
Anti-Ms CD44, IM7, PE, 25 | 60068PE.1 | 25 tests |
Anti-Ms CD44, IM7, PE | 60068PE | 100 tests |
Anti-Ms CD44, IM7, FI, 500µg | 60068FI | 500 µg |
Anti-Ms CD44, IM7, FI, 50µg | 60068FI.1 | 50 µg |
Anti-Ms CD44, IM7, BT, 50 | 60068BT.1 | 50 µg |
Anti-Ms CD44, IM7, BT | 60068BT | 500 µg |
Anti-Ms CD44, IM7, AZ, 100µg | 60068AZ | 100 µg |
Anti-Ms CD44, IM7, AZ, 25µg | 60068AZ.1 | 25 µg |
Anti-Ms CD44, IM7, AD, 25 | 60068AD.1 | 25 µg |
Anti-Ms CD44, IM7, AD | 60068AD | 100 µg |
Anti-Ms CD44, IM7, 50µg | 60068.1 | 50 µg |
Anti-Ms CD44, IM7 | 60068 | 500 µg |
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重庆市寰宇安泰生物科技有限公司