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Stemcell 60109PS.1 Anti-Mouse CD62L (L-Selectin) Antibody, Clone MEL-14
Product Overview
The MEL-14 antibody reacts with murine CD62L (L-Selectin or LECAM-1), an ~74 - 95 kDa type I glycoprotein expressed on the surface of a majority of leukocytes. CD62L mediates leukocyte-endothelial cell interactions through its association with ligands such as CD34, glyCAM-1, MAdCAM-1 and PSGL-1. It functions to facilitate lymphocyte rolling on the vascular endothelium, trafficking of lymphocytes to the lymph nodes, and homing of lymphocytes and neutrophils to sites of inflammation. Murine CD62L is expressed on most thymocytes, the highest expression levels being found on subsets of immunocompetent or dividing progenitor cells, as well as on neutrophils, eosinophils, monocytes, and subsets of B, T and NK cells. The MEL-14 antibody may be used in concert with antibodies to other cell surface markers to distinguish naïve, memory and effector T cells. The MEL-14 antibody has been shown to block migration of lymphocytes to lymph nodes and to inhibit leukocyte rolling.
Subtype:一抗
Target Antigen:CD62L (L-selectin)
Reactive Species:小鼠
Conjugation:Alexa Fluor 488; APC; 生物素; FITC; PE; PerCP-Cyanine5.5; 未结合
Host Species:大鼠
Cell Type:T细胞
Application:CyTOF; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀
Area of Interest:免疫学
Clone:MEL-14
Gene ID:20343
Isotype:IgG2a, kappa
Related products
Description | Catalog # | Format |
Anti-Ms CD62L, MEL-14, UC, 500µg | 60109 | 500 µg |
Anti-Ms CD62L, MEL-14, UC, 100µg | 60109.1 | 100 µg |
Anti-Ms CD62L, MEL-14, PS, 100µg | 60109PS | 100 µg |
Anti-Ms CD62L, MEL-14, PS, 25µg | 60109PS.1 | 25 µg |
Anti-Ms CD62L, MEL-14, PE, 100µg | 60109PE | 100 µg |
Anti-Ms CD62L, MEL-14, PE, 25µg | 60109PE.1 | 25 µg |
Anti-Ms CD62L, MEL-14, FI, 500µg | 60109FI | 500 µg |
Anti-Ms CD62L, MEL-14, FI, 100µg | 60109FI.1 | 100 µg |
Anti-Ms CD62L, MEL-14, FI, 25µg | 60109FI.2 | 25 µg |
Anti-Ms CD62L, MEL-14, BT, 500µg | 60109BT | 500 µg |
Anti-Ms CD62L, MEL-14, BT, 50µg | 60109BT.1 | 50 µg |
Anti-Ms CD62L, MEL-14, AZ, 100µg | 60109AZ | 100 µg |
Anti-Ms CD62L, MEL-14, AZ, 25µg | 60109AZ.1 | 25 µg |
Anti-Ms CD62L, MEL-14, AD, 100µg | 60109AD | 100 µg |
Anti-Ms CD62L, MEL-14, AD, 25µg | 60109AD.1 | 25 µg |
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