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Stemcell 60036PE Anti-Mouse CD150 Antibody, Clone TC15-12F12.2
Product Overview
The TC15-12F12.2 antibody reacts with CD150 (signaling lymphocyte activation molecule or SLAM), an ~75 kDa type I transmembrane glycoprotein that plays multiple roles in the immune response by serving as a cell adhesion molecule and/or coreceptor. It is differentially expressed by T cells, immature thymocytes, B cells, dendritic cells, macrophages and endothelial cells. The expression pattern differs according to cell type and activation status. Expression is rapidly induced upon activation of T cells, B cells and dendritic cells, with synthesis by T cells being maintained on Th1 but not Th2 clones. CD150-mediated co-stimulation of TCR-activated T cells enhances the production of IFN-γ by Th1 cells, a response that can be augmented by binding of the TC15-12F12.2 antibody. CD150 is thought to mediate signal transduction by associating with the intracellular protein tyrosine phosphatase, SHP-2. CD150 also has functions in hematopoietic cell development and is a useful marker for detection of multipotent hematopoietic stem cells (in concert with other markers such as CD48 and CD41). CD150 is not expressed on non-multipotent hematopoietic progenitor cells.
Subtype:一抗
Target Antigen:CD150 (SLAM)
Reactive Species:小鼠
Conjugation:Alexa Fluor 488; APC; 生物素; PE; PE-Cyanine7; 未结合
Host Species:仓鼠; 大鼠
Cell Type:造血干细胞和祖细胞
Application:流式细胞术; 功能检测; 免疫荧光; 免疫组化; 免疫沉淀
Area of Interest:干细胞生物学
Clone:TC15-12F12.2
Gene ID:27218
Isotype:IgG2a, lambda
Related products
Description | Catalog # | Format |
Anti-Ms CD150, TC15-12F12.2, PE, 25 | 60036PE.1 | 25 µg |
Anti-Ms CD150, TC15-12F12.2, PE | 60036PE | 100 µg |
Anti-Ms CD150, TC15-12F12.2, BT, 100µg | 60036BT | 100 µg |
Anti-Ms CD150, TC15-12F12.2, BT, 25µg | 60036BT.1 | 25 µg |
Anti-Ms CD150, TC15-12F12.2, AZ, 100µg | 60036AZ | 100 µg |
Anti-Ms CD150, TC15-12F12.2, AZ, 25µg | 60036AZ.1 | 25 µg |
Anti-Ms CD150, TC15-12F12.2, AD, 25 | 60036AD.1 | 25 µg |
Anti-Ms CD150, TC15-12F12.2, AD | 60036AD | 100 µg |
Anti-Ms CD150, TC15-12F12.2, 50µg | 60036.1 | 50 µg |
Anti-Ms CD150, TC15-12F12.2 | 60036 | 500 µg |
Anti-Ms CD138, 281-2, UC, 500µg | 60035 | 500 µg |
Anti-Ms CD138, 281-2, UC, 25µg | 60035.1 | 25 µg |
Anti-Ms CD138, 281-2, PE, 200µg | 60035PE | 200 µg |
Anti-Ms CD138, 281-2, PE, 25µg | 60035PE.1 | 25 µg |
Anti-Ms CD138, 281-2, BT, 500µg | 60035BT | 500 µg |
Anti-Ms CD138, 281-2, BT, 50µg | 60035BT.1 | 50 µg |
Anti-Ms CD138, 281-2, AZ, 100µg | 60035AZ | 100 µg |
Anti-Ms CD138, 281-2, AZ, 25µg | 60035AZ.1 | 25 µg |
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