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Stemcell 60038FI.1 Anti-Mouse EPCR Antibody, Clone RMEPCR1560
Product Overview
The RMEPCR1560 antibody reacts with the endothelial protein C receptor (EPCR or CD201), an ~25 kDa type I transmembrane glycoprotein expressed by endothelial cells, subsets of hematopoietic stem cells (HSCs) and dendritic cells, and several malignant cell lines. It is also found in a soluble form in plasma. EPCR exhibits homology with the MHC class 1/CD1 protein family. EPCR binds Protein C and activated Protein C, thus augmenting Protein C activation by the thrombin-thrombomodulin complex and regulating blood coagulation and inflammation. EPCR protein expression has been detected on ~1.5% of mouse bone marrow cells. Purified EPCR+ cells are highly enriched for HSC activity, as evidenced by high in vivo repopulation activity. Moreover, EPCR expression is associated with the stem cell activity of bone marrow cell populations isolated using conventional markers, indicating the usefulness of EPCR as a single marker for the identification of mouse HSCs.
Subtype:一抗
Target Antigen:EPCR (CD201)
Reactive Species:小鼠
Conjugation:生物素; FITC; PE; 未结合
Host Species:大鼠
Cell Type:内皮细胞; 造血干细胞和祖细胞
Application:细胞分离; 流式细胞术; 功能检测; 免疫组化; Western印迹法
Area of Interest:内皮细胞生物学; 干细胞生物学
Clone:RMEPCR1560
Gene ID:19124
Isotype:IgG2b, kappa
Related products
Description | Catalog # | Format |
Anti-Ms EPCR, RMEPCR1560, PE, 25 | 60038PE.1 | 0.125 mL |
Anti-Ms EPCR, RMEPCR1560, PE | 60038PE | 0.5 mL |
Anti-Ms EPCR, RMEPCR1560, FI, 25 | 60038FI.1 | 0.5 mL |
Anti-Ms EPCR, RMEPCR1560, FI | 60038FI | 2 mL |
Anti-Ms EPCR, RMEPCR1560, BT | 60038BT | 0.5 mL |
Anti-Ms EPCR, RMEPCR1560 | 60038 | 0.2 mL |
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