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Stemcell 60027PE Anti-Mouse F4/80 Antibody, Clone BM8
Product Overview
The BM8 antibody reacts with the F4/80 antigen (also termed Ly-71 in mouse and EMR-1 in human), an ~160 kDa transmembrane glycoprotein belonging to the EGF-TM7 family of G-protein-coupled receptors. F4/80 is considered a marker of choice for the identification of mature tissue macrophages, being broadly but variably expressed by this cell type in the liver (Kupffer cells), skin (Langerhans cells), bone marrow stroma, pancreas, thymus, spleen (red pulp), lung, and other tissues. It is also expressed by circulating monocytes, eosinophils and a subset of dendritic cells. F4/80 expression levels increase following activation of macrophages. F4/80 is reportedly the only macrophage marker suitable for distinguishing destructive from non-destructive inflammatory processes in the pancreas. The protein is thought to play a role in the generation of CD8+ regulatory T cells involved in immune tolerance.
This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse Monocyte Enrichment Kit (Catalog #19761) and EasySep™ Mouse CD11b Positive Selection Kit (Catalog #18770).
Subtype:一抗
Target Antigen:F4/80
Reactive Species:人; 小鼠
Conjugation:Alexa Fluor 488; APC; 生物素; FITC; PE; PerCP-Cyanine5.5; 未结合
Host Species:大鼠
Cell Type:单核细胞; 其他
Application:细胞分离; ELISA; 流式细胞术; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀; Western印迹法
Area of Interest:免疫学
Clone:BM8
Gene ID:13733
Isotype:IgG2a, kappa
Related products
Description | Catalog # | Format |
Anti-Ms F4/80, BM8, PS, 100µg | 60027PS | 100 µg |
Anti-Ms F4/80, BM8, PS, 25µg | 60027PS.1 | 25 µg |
Anti-Ms F4/80, BM8, PE, 25 | 60027PE.1 | 25 µg |
Anti-Ms F4/80, BM8, PE | 60027PE | 100 µg |
Anti-Ms F4/80, BM8, FI, 500µg | 60027FI | 500 µg |
Anti-Ms F4/80, BM8, FI, 50µg | 60027FI.1 | 50 µg |
Anti-Ms F4/80, BM8, BT, 500µg | 60027BT | 500 µg |
Anti-Ms F4/80, BM8, BT, 50µg | 60027BT.1 | 50 µg |
Anti-Ms F4/80, BM8, AZ, 100µg | 60027AZ | 100 µg |
Anti-Ms F4/80, BM8, AZ, 25µg | 60027AZ.1 | 25 µg |
Anti-Ms F4/80, BM8, AD, 25 | 60027AD.1 | 25 µg |
Anti-Ms F4/80, BM8, AD | 60027AD | 100 µg |
Anti-Ms F4/80, BM8 | 60027 | 500 µg |
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