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Stemcell 60103FI.1 Anti-Mouse NK1.1 (CD161), Clone PK136
Product Overview
The PK136 antibody reacts with murine NK1.1 (CD161), an ~80 kDa homodimeric type 2 transmembrane glycoprotein and C-type lectin receptor expressed on NK cells, NK-T cells and rare subsets of T cells and monocytes in select strains of mice. NK1.1 is encoded by the Klrb1b and Klrb1c genes, which specify CD161b and CD161c polypeptides, respectively. CD161b is expressed only by Swiss NIH and SJL mice, and CD161c by certain strains such as C57BL, FVB/N and NZB (but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, NOD, SJL or 129). NK1.1 has functional roles in modulating several processes, including the activation and proliferation of NK cells, induction of interferon-γ production, and release of cytotoxic granules. Its expression on the cell surface is specifically upregulated by IL-12. For detection of NK cells in NK1.1- strains the antibody clone DX5 is recommended (Catalog #60020). DX5 recognizes CD49b (integrin α2), another commonly employed NK cell marker.
Subtype:一抗
Target Antigen:NK1.1 (CD161)
Reactive Species:小鼠
Conjugation:Alexa Fluor 488; APC; 生物素; FITC; PE; PerCP-Cyanine5.5; 未结合
Host Species:小鼠
Cell Type:NK细胞
Application:细胞分离; CyTOF; 去除; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀
Area of Interest:免疫学
Clone:PK136
Gene ID:17059
Isotype:IgG2a, kappa
Related products
Description | Catalog # | Format |
Anti-Ms NK1.1, PK136, PS, 100µg | 60103PS | 100 µg |
Anti-Ms NK1.1, PK136, PS, 25µg | 60103PS.1 | 25 µg |
Anti-Ms NK1.1, PK136, PE, 200µg | 60103PE | 200 µg |
Anti-Ms NK1.1, PK136, PE, 50µg | 60103PE.1 | 50 µg |
Anti-Ms NK1.1, PK136, FI, 500µg | 60103FI | 500 µg |
Anti-Ms NK1.1, PK136, FI, 50µg | 60103FI.1 | 50 µg |
Anti-Ms NK1.1, PK136, BT, 500µg | 60103BT | 500 µg |
Anti-Ms NK1.1, PK136, BT, 50µg | 60103BT.1 | 50 µg |
Anti-Ms NK1.1, PK136, AZ, 100µg | 60103AZ | 100 µg |
Anti-Ms NK1.1, PK136, AZ, 25µg | 60103AZ.1 | 25 µg |
Anti-Ms NK1.1, PK136, AD, 100µg | 60103AD | 100 µg |
Anti-Ms NK1.1, PK136, AD, 25µg | 60103AD.1 | 25 µg |
Anti-Ms NK1.1, PK136, 500µg | 60103 | 500 µg |
Anti-Ms NK1.1, PK136, 50µg | 60103.1 | 50 µg |
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