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Stemcell 60032BT Anti-Mouse Sca1 Antibody, Clone E13-161.7
Product Overview
The E13-161.7 antibody reacts with Sca1 (Stem Cell Antigen-1 or Ly-6A/E), an 18 kDa GPI-linked protein belonging to the lymphocyte activation protein-6 (Ly-6) family. Sca1 is expressed on the surface of hematopoietic stem and progenitor cells, myeloid cells, and peripheral B and T lymphocytes. Sca1 is expressed by mice with either the Ly-6.1 or Ly-6.2 allotypes but the pattern of expression differs in the circulating cell population according to the allotype. Ly-6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) possess relatively high numbers of Sca1+ resting lymphocytes compared to Ly-6.1 strains (e.g. A, BALB/c, CBA, C3H/He, DBA/1, NZB). Sca1 expression levels are strongly upregulated in all strains upon cellular activation. Sca1 is involved in the regulation of T and B cell responses and is believed to play roles in the differentiation, proliferation, and survival of a variety of stem cells. Sca1 has emerged as a phenotypic marker of choice for identifying and isolating hematopoietic stem and progenitor cells.
This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse SCA1 Biotin Positive Selection Kit (Catalog #18856).
Subtype:一抗
Target Antigen:Sca1 (Ly-6A/E)
Reactive Species:小鼠
Conjugation:Alexa Fluor 488; APC; 生物素; FITC; PE; 未结合
Host Species:大鼠
Cell Type:造血干细胞和祖细胞; 乳腺细胞
Application:细胞分离; 流式细胞术; 功能检测; 免疫细胞化学; 免疫荧光; 免疫组化; 免疫沉淀
Area of Interest:上皮细胞生物学; 干细胞生物学
Clone:E13-161.7
Gene ID:110454
Isotype:IgG2a, kappa
Related products
Description | Catalog # | Format |
Anti-Ms Sca1, E13-161.7, PE, 50 | 60032PE.1 | 50 µg |
Anti-Ms Sca1, E13-161.7, PE | 60032PE | 200 µg |
Anti-Ms Sca1, E13-161.7, FI, 500µg | 60032FI | 500 µg |
Anti-Ms Sca1, E13-161.7, FI, 50µg | 60032FI.1 | 50 µg |
Anti-Ms Sca1, E13-161.7, BT, 500µg | 60032BT | 500 µg |
Anti-Ms Sca1, E13-161.7, AZ, 100µg | 60032AZ | 100 µg |
Anti-Ms Sca1, E13-161.7, AZ, 25µg | 60032AZ.1 | 25 µg |
Anti-Ms Sca1, E13-161.7, AD, 25 | 60032AD.1 | 25 µg |
Anti-Ms Sca1, E13-161.7, AD | 60032AD | 100 µg |
Anti-Ms Sca1, E13-161.7 | 60032 | 500 µg |
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