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Stemcell 60104AD Anti-Mouse TCR Gamma/Delta Antibody, Clone GL3
Product Overview
The GL3 antibody reacts with the δ chain of the murine T cell receptor γ/δ (TCRγ/δ or TCR gamma/delta), a subtype of the TCR involved in the recognition of both peptide and lipid antigens. TCRγ/δ comprises a heterodimer (~ 80 kDa in humans) of disulfide-linked γ and δ subunits that associates with CD3 on the cell surface. It is a member of the immunoglobulin superfamily. TCRγ/δ is expressed on a subpopulation of T cells in the circulation but may be found on up to 50% of the T cells in epithelial cell-rich tissues. These cells have roles in oral and tumor-associated tolerance as well as autoimmune disease and have been described as a link between the adaptive and innate immune responses. Once activated, they secrete effector cytokines in a subtype- and context-specific manner. Most γ/δ T cells are CD4-/CD8-, though some express CD8. The GL3 antibody recognizes an epitope in the constant region of the δ chain and can reportedly activate TCRγ/δ+ cells.
Subtype:一抗
Target Antigen:T Cell Receptor Gamma/Delta
Reactive Species:小鼠
Conjugation:Alexa Fluor 488; APC; 生物素; FITC; PE; 未结合
Host Species:仓鼠
Cell Type:T细胞; T细胞，其他亚型
Application:细胞分离; 去除; 流式细胞术; 功能检测; 免疫荧光; 免疫组化; 免疫沉淀; 中和及阻滞
Area of Interest:免疫学
Clone:GL3
Gene ID:110066/110067
Isotype:IgG2, kappa
Related products
Description | Catalog # | Format |
Anti-Ms TCR Gamma/Delta, GL3, PE, 100µg | 60104PE | 100 µg |
Anti-Ms TCR Gamma/Delta, GL3, PE, 25µg | 60104PE.1 | 25 µg |
Anti-Ms TCR Gamma/Delta, GL3, FI, 200µg | 60104FI | 200 µg |
Anti-Ms TCR Gamma/Delta, GL3, FI, 50µg | 60104FI.1 | 50 µg |
Anti-Ms TCR Gamma/Delta, GL3, BT, 500µg | 60104BT | 500 µg |
Anti-Ms TCR Gamma/Delta, GL3, BT, 100µg | 60104BT.1 | 100 µg |
Anti-Ms TCR Gamma/Delta, GL3, BT, 50µg | 60104BT.2 | 50 µg |
Anti-Ms TCR Gamma/Delta, GL3, AZ, 100µg | 60104AZ | 100 µg |
Anti-Ms TCR Gamma/Delta, GL3, AZ, 25µg | 60104AZ.1 | 25 µg |
Anti-Ms TCR Gamma/Delta, GL3, AD, 100µg | 60104AD | 100 µg |
Anti-Ms TCR Gamma/Delta, GL3, AD, 25µg | 60104AD.1 | 25 µg |
Anti-Ms TCR Gamma/Delta, GL3, 100µg | 60104 | 100 µg |
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