Anti-Phospho-SHIP Antibody, Polyclonal

Rabbit polyclonal antibody against human, mouse phosphoSHIP

产品描述

• Phospho-SHIP is highly phosphorylated form of SHIP. SH2-containing inositol phosphatase (SHIP) is a 145 kDa hematopoietic-restricted protein that becomes tyrosine phosphorylated and associated with the adaptor protein, Shc, following cytokine, growth factor, chemokine, and immunoreceptor stimulation. SHIP also hydrolyzes the critical phosphatidylinositol (PI)-3-kinase (PI3K)-generated second messenger, PI-3,4,5-P3 (PIP3), to PI-3,4-P2 1,2 and therefore acts as an important negative regulator of the PI3K pathway. This antibody reacts with mouse and human tyrosine phosphorylated SHIP.
• Components:

Subtype:

一抗

Target Antigen:

PhosphoSHIP

Reactive Species:

人; 小鼠

Conjugation:

未结合

Host Species:

兔

Cell Type:

粒细胞及其亚型; 淋巴细胞; 髓系细胞

Application:

流式细胞术; 免疫印迹; 免疫荧光; 免疫沉淀

Area of Interest:

免疫学

Clone:

Not applicable

Gene ID:

3635 (human), 16331 (mouse)

Isotype:

Not applicable

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