Santa Cruz sc-202951  Ampicillin sodium salt, cell culture grade

产品编号 sc-202951 | santa cruz

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• 产品描述
• Ampicillin is a β-lactam antibiotic within the penicillin family. As a member of this family, Ampicillin is susceptible to β-lactamase, which hydrolyzes the β-lactam ring. This broad spectrum antibiotic is effective against gram-positive, gram-negative bacteria and anaerobic bacteria. Ampicillin is widely used in cell culture as a selective agent. As an antibiotic, Ampicillin binds to penicillin binding proteins (PBPs) on a susceptible organism and inhibits cell wall synthesis by interfering with the enzymes responsible for the formation of the organisms cell wall. After binding to the PBPs, Ampicilin acts as a structural analogue of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme and thereby prevents the cross-linking of the peptidoglycan of the cell wall necessary for the growth of the bacterium. Potency: ≥ 845 µg Ampicillin/mg (anhydrous)

参考文献

• Yang, W., et al. 2001. Protein Expr. Purif. 22: 472-478. PMID: 114830112. Rafailidis, P.I., et al. 2007. Drugs. 67: 1829-1849. PMID: 177229533. Joseleau-Petit, D., et al. 2007. J. Bacteriol. 189: 6512-6520. PMID: 17586646

用法 :

100 µg/ml for cell culture usage

规划 :

≥ 845 µg Ampicillin/mg (anhydrous)

外观 :

Powder

物理状态 :

Solid

溶解度 :

Soluble in water (50 mg/ml), chloroform, and acetone (1:50).

保存 :

Store at -20° C

熔点 :

215° C

折射率 :

n²⁰_D 1.68 (Predicted)

IC50 :

Klebsiella pneumoniae: IC₅₀ = 0.08 ug.mL-1; Staphylococcus aureus: IC₅₀ = 0.74 ug.mL-1

Ki 数据 :

PEPT2: K_i= 1.3 mM (human); Oligopeptide transporter, kidney isoform: K_i= 1.3 mM (rat)

公司介绍

• SANTA CRUZ公司是全球最大的抗体生产厂商之一，目前公司提供二万余种研究用的第一抗体，几乎覆盖了目前生命科学研究的各个最新领域，其每种抗体又有多个克隆可以选择，还提供一些对应蛋白标准品及相关产品，如ABC试剂盒，各种标记二抗，Western试剂盒，蛋白分子量Marker，核抽提物等，为免疫学研究工作提供了极大的方便。
• Uante,您的科研物资战略合作伙伴！

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