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BD Pharmingen™ 560944 FITC Mouse Anti-Human HLA-DR Clone G46-6 (RUO)
产品编号 560944|BD Pharmingen™
FITC Mouse Anti-Human HLA-DR Clone G46-6 (RUO)
产品描述
Brand
BD Pharmingen™
Vol. Per Test
20 µl
Isotype
Mouse IgG2a, κ
Reactivity
Human (QC Testing) Rhesus, Cynomolgus, Baboon, Dog (Tested in Development)
Application
Flow cytometry (Routinely Tested)
Storage Buffer
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Regulatory Status
RUO
Sizes
Catalog No.
560944
List Price
¥ 1,538.00
Your Price
Unit
EA (1 Each)
产品详情
DESCRIPTION
The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
FORMAT
Format
FITC
Excitation Source
Blue 488 nm
Excitation Max
494 nm
Emission Max
520 nm
FITC, fluorescein isothiocyanate, is a fluorochrome with a molecular weight of 389 Da. FITC is sensitive to pH changes and photobleaching. Due to nearly identical excitation and emission properties but different spillover characteristics, FITC and Alexa Fluor® 488 cannot be used simultaneously. FITC is relatively dim and should be reserved for highly expressed markers whenever possible.
Other Formats →
APC
APC-H7
APC-R700
Alexa Fluor® 700
BB515
BUV395
BUV661
BV421
BV480
BV510
BV605
BV650
BV711
BV786
NA/LE
PE
PE-CF594
PE-Cy™5
PE-Cy™7
PerCP-Cy™5.5
SUGGESTED COMPANION PRODUCTS
Cat No. | Description | Size |
555573 | FITC Mouse IgG2a, κ Isotype Control RUO | 100 Tests |
RESOURCES & TOOLS
Spectrum Viewer
Panel Designer
Download TDS
PREPARATION AND STORAGE
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
PRODUCT NOTICES
This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-µl experimental sample (a test).
Since applications vary, each investigator should titrate the reagent to obtain optimal results.
Please refer to www.bdbiosciences.com/pharmingen/protocols for technical protocols.
Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Source of all serum proteins is from USDA inspected abattoirs located in the United States.
公司简介
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BD目前经营产品超过一万余种，是全球知名的医用一次性产品供应商。公司上市的所有产品均遵循同行业最高标准，并通过ISO国际质量认证。
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BD公司的业务共分为三大类: BD医疗, BD生物科学, BD诊断
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