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Stemcell 72824 PluriSIn-1
Product Overview
PluriSIn-1 is an N-acyl phenylhydrazine derivative that inhibits stearoyl-CoA desaturase, a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (Ben-David et al.).
DIFFERENTIATION
· Selectively eliminates undifferentiated human embryonic stem (ES) and induced pluripotent stem (iPS) cells while sparing differentiated cells, and prevents teratoma formation in transplanted mice (Ben-David et al.).
· Induces apoptosis of Nanog-positive iPS cells in vitro, while leaving iPS cell-derived cardiomyocytes unaffected (Zhang et al.).
CAS Number:91396-88-2
Alternative Names:N’-phenyl-hydrazine-Isonicotinic acid; NSC 14613
Chemical Formula:C₁₂H₁₁N₃O
Molecular Weight:213.2 g/mol
Purity:≥ 95%
Pathway:油酸
Target:SCD1
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