综合电商模板

重组人 HGF蛋白（Recombinant Human HGF Protein），GMP级

产品货号：GMP-TL765

产品描述（Description）

HGF is a hetrodimer molecule composed of 69-kDa alpha-subunit and 34-beta-subunit. HGF is a potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. HGF mRNA and HGF activity increase markedly in the liver of rats after various liver injuries such as hepatitis, ischemia, physical crush, and partial hepatectomy. Production of HGF in the liver occurs in Kupffer cells and sinusoidal endothelial cells, but not in parenchymal hepatocytes. HGF mRNA is also markedly increased even in the intact lung, kidney, and spleen after injuries of the liver. Therefore, HGF may act as a trigger for liver regeneration through two mechanisms: a paracrine mechanism and an endocrine mechanism. Moreover, HGF mRNA increases markedly in the kidney after various renal injuries, thus it suggests that HGF may act not only as a hepatotropic factor but also as a renotropic factor. HGF stimulates growth of various epithelial cells, including renal tubular cells (Mitogen). It is worth noting that HGF strongly enhances motility of epithelial cells (Motogen) and induces epithelial tubule formation (Morphogen), while it strongly inhibits growth of several tumor cells. All these findings indicate that HGF may have important roles in organogenesis, morphogenesis, carcinogenesis, as well as in organ regeneration.

表达宿主（Expression host）

HEK293细胞

同义词（Synonyms）

Hepatocyte growth factor ;DFNB39 Protein, Human; F-TCF Protein, Human; F-TCFB Protein, Human; HGFB Protein, Human; HPTA Protein, Human; SF Protein, Human.

蛋白序列（Protein Sequence）

DNA序列编码人HGF（P14210）表达带有His标签在C末端

分子量（Molecular Weight）

重组人HGF蛋白包含742个氨基酸，预测分子量为84.8kD

纯度（Purity）

>90%，采用 SDS-PAGE 凝胶分析

内毒素（Endotoxin）

<0.1EU/μg

生物活性（Biological Activity）

纯化方式（Purification Method）

层析纯化

性状（Character）

白色疏松体

使用说明（Instructions）

冻干制剂可在 2~8℃保存 24 个月。

如需分装，可用注射用水、生理盐水、培养基或 PBS 溶解，溶解后分装成小份，置于-20℃保存 期 6 个月，-80℃保存期 12 个月，稀释后浓度不低于 100μg/mL。避免反复冻融。

注意：所有产品“仅用于非临床科研用途，不用于诊断、治疗、临床或其他用途”！

重庆市寰宇安泰生物科技有限公司【Chongqing Uante Biological Technology Co.,Ltd.】专注于生命科学科研试剂、耗材、仪器仪表等销售与科研技术服务。主营产品覆盖分子生物学、细胞生物学、免疫学、生物制药、诊断试剂研发、干细胞研究、美容抗衰等众多领域。代理或经销数十家知名品牌产品，如：OriGen、StemCell、同立海源、CSTI、GEB、PALL、Sigma、Thermo Fisher、Lonza、BD等。面向全国销售，业务范围涉及：北京、天津、上海、重庆、河北石家庄、山西太原、内蒙古呼和浩特、辽宁沈阳、吉林长春、黑龙江哈尔滨、江苏南京、浙江杭州、安徽合肥、福建福州、江西南昌、山东济南、河南郑州、湖北武汉、河南长沙、广东广州、广西南宁、海南海口、四川成都、贵州贵阳、云南昆明、西藏拉萨、陕西西安、甘肃兰州、青海西宁、宁夏银川、乌鲁木齐等多省\市\区\自治州；将为广大科研用户在生命科学研究领域，提供高品质科研产品服务。公司秉承“诚信为本、服务至上”的管理理念，在未来的工作中，不断努力，奋发进取，力争成为您的科研物资战略合作优选伙伴！为生命科学领域的一线工作者提供最强有力的基础与支撑。

Uante,您的科研物资战略合作伙伴！

重庆市寰宇安泰生物科技有限公司

联系电话：023-67946738/17774916696

QQ:201719961   邮箱：info@uantebio.com