StemRD JAG-1-pep JAG-1 protein active peptide fragment

产品编号JAG-1-pep | StemRD

JAG-1 蛋白活性片断

产品描述

The Notch pathway is an important pathway in stem cell functions. Jagged-1 is a ligand for Notch receptors. This peptide with a sequence of CDDYYYGFGCNKFCRPR has been shown to mimic the function of full-length Jagged-1, and therefore, can be used as an agonist to activate the Notch pathway. Ref: Nickoloff et al, Cell Death Different, 2002; Sato T et al, Nature, 2009
公司简介

StemRD Inc. is located in the San Francisco Bay Area, we specialize in producing premier research reagents for the stem cell research community. Our mission is to empower stem cell R&D through innovative technologies. Our proprietary technology in protein expression and purification has allowed efficient production of several important factors, such as WNT, Hedgehog, TGF-ß family members and Differentiation Kits, that are difficult to obtain by conventional methods.

StemRD 是美国一家聚焦于尖端干细胞研究的公司，拥有蛋白表达和纯化方面的专利技术。拥有被美国FDA认证的可用于GMP生产治疗型多肽的设施。StemRD的实验室拥有包括组织培养、细胞处理、超离心、超过滤、FPLC、HPLC和LC/MS等一系列先进设备。其中干细胞研究用生长/分化因子、小分子化合物均包括目前研究较多的WNT/β-catenin、TGF-β、Hedgehog、Notch等信号通路等。