Keratin 5 Polyclonal Antibody, Purified

￥ 5236.00

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Biolegend(Covance) 905501 Keratin 5 Polyclonal Antibody, Purified

产品编号 905501| Biolegend(Covance)

产品描述

Intended Use:	In Vitro Diagnostic (IVD). Use in immunohistochemistry (IHC) test methods only.The polyclonal antibody Poly19055 is used for the in vitro examination of human biological samples using immunohistochemistry (IHC) methods for the qualitative identification of Keratin 5. The clinical interpretation of any staining or its absence should be complemented by morphological studies and proper controls and should be evaluated within the context of the patient's clinical history and other diagnostic tests by a qualified pathologist.
Clone:	Poly19055 (See other available formats)
Isotype:	Rabbit Polyclonal
Reactivity:	Human, Mouse. Rat, Dog, Primate
Immunogen:	This monospecific polyclonal antibody was raised against a peptide sequence derived from the C-terminus of the mouse keratin 5 protein.
Formulation:	Phosphate-buffered solution + 0.03% Thimerosal.
Preparation:	The antibody was purified by peptide affinity chromatography.
Concentration:	1 mg/ml
Storage & Handling:	When stored at ≤ -20°C, product is stable until the date shown on the label. Avoid repeated freeze-thaw cycles to prevent denaturing the antibody. If thawed and stored at 2-8°C, product is stable for 24 months from the date of thaw or until the expiry date on the label, whichever comes first.
Application:	IHC
Recommended Usage:	Each lot of this antibody is quality control tested by immunohistochemical staining.The optimal working dilution should be determined for each specific assay condition.• IHC: 1:2,000-4,000 with either biotin based detection systems such as USA Ultra Streptavidin Detection (Cat. No. 929501).Tissue Sections: Paraffin-embedded tissues, frozen tissuesPretreatment: For optimal staining, the sections should be pretreated with an antigen unmasking solution such as Citrate Buffer Retrieval solution (Cat. No. 928502, 928602).Incubation: 60 minutes at room temperature
ApplicationNotes:	This antibody is effective in immunohistochemistry (IHC).
ApplicationReferences:	1. Hübner A, et al. JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate. PNAS, 109: 12046-12051, Jul 2012. [IHC] PubMed 2. Kierszenbaum AL, Rivkin E, Tres LL. Acroplaxome, an F-actin-keratin-containing plate, anchors the acrosome to the nucleus during shaping of the spermatid head. Mol Biol Cell 14(11):4628-40, 2003. [IHC] PubMed 3. Hu Y, Baud V, Oga T, Kim KI, Yoshida K, Karin M. IKKalpha controls formation of the epidermis independently of NF-kappaB.Nature 410:710-714, 2001.4. Yuspa SH, Kilkenny AD, Steinert PM, Roop DR. Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in-vitro. J Cell Biol 109:1207-1217, 1989.5. Roop DR, Cheng CK, Titterington L, Meyers CA, Stanley JR, Steinert PM, Yuspa SH. Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies. J Biol Chem 259:8037-8040, 1984. 6. Liang Y, 2011 Patholog Res Int. 2011:936794. (IHC) PubMed
	Publication Library
RRID:	AB_2565050 (BioLegend Cat. No. 905501)

公司简介

Covance主要业务是研发和生产各种抗体，涉及领域包括：神经生物学、免疫病理学、细胞生物学、表位抗体和免疫组化等方面的科研试剂。特色产品是免疫组化的体外诊断试剂。美国 BioLegend 公司于圣地亚哥时间2014年8月29日收购了位于马萨诸塞州戴德姆的科文斯（Covance）旗下的科文斯抗体服务公司（Covance Antibody Services Inc.）。科文斯抗体服务公司主要业务是研发和生产各种抗体，涉及领域包括:神经生物学、免疫病理学、细胞生物学、表位抗体和免疫组化等方面的科研试剂。这些用于免疫组化的体外诊断试剂（IVD）对于 BioLegend 公司目前的科研试剂产品线是一个很好的补充和扩展。科文斯抗体的客户将享有与 BioLegend 当前客户同样的优质服务和高性价比的产品。

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市场价

￥5236.00

价格

￥5236.00

品牌

Biolegend(Covance)

型号

905501