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Biolegend(Covance) 825701 Purified anti-α-Synuclein Phospho (Ser129) Antibody
产品编号 825701| Biolegend(Covance)
产品描述
Clone: | P-syn/81A (See other available formats) |
Isotype: | Mouse IgG2a |
Reactivity: | Human, Mouse, Rat (by sequence identity) |
Immunogen: | This monoclonal antibody was raised against a synthetic peptide corresponding to amino acids 124 - 134 of α-synuclein, phosphorylated at Serine 129, and conjugated to KLH via a C-terminal Cysteine. |
Formulation: | Phosphate-buffered solution with 0.1% azide. |
Preparation: | The antibody was purified by affinity chromatography. |
Concentration: | 1 mg/ml |
Storage & Handling: | Store at 2-8°C. Do not freeze. |
Application: | IHC - Quality testedIF - Reported in the literature |
Recommended Usage: | Each lot of this antibody is quality control tested by immunohistochemical staining.The optimal working dilution should be determined for each specific assay condition. • IHC: 1:500 - 1:1000Tissue: Formalin-fixed Paraffin-embedded sectionsPretreatment: 70% Formic AcidPrimary Incubation: 24 hours at 4°C |
ApplicationNotes: | This antibody is effective in immunohistochemistry (IHC) and immunofluorescence (IF)1,2.81A is a mAb that is specific to alpha synuclein that has been phosphorylated on serine 129. IHC Positive Control: Diseased Human Brain (PD) |
ApplicationReferences: | 1. Waxman, Elisa, et. al. Specificity and Regulation of Casein Kinase/MediatedPhosphorylation of α-Synuclein. J Neuropathol Exp Neurol, 67(5): 402-416, May 2008.2. Lim Y, et al. 2011. J. Neurosci. 31:10076. (IF) 3. Volpicelli-Daley LA, et al. 2014. Mol. Biol. Cell. 25:4010. (IF)PubMed 4. Doppler K, et al. 2016. Brain. 139: e5. PubMed |
Publication Library | |
RRID: | AB_2564891 (BioLegend Cat. No. 825701) |
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Covance主要业务是研发和生产各种抗体，涉及领域包括：神经生物学、免疫病理学、细胞生物学、表位抗体和免疫组化等方面的科研试剂。特色产品是免疫组化的体外诊断试剂。美国 BioLegend 公司于圣地亚哥时间2014年8月29日收购了位于马萨诸塞州戴德姆的科文斯（Covance）旗下的科文斯抗体服务公司（Covance Antibody Services Inc.）。科文斯抗体服务公司主要业务是研发和生产各种抗体，涉及领域包括:神经生物学、免疫病理学、细胞生物学、表位抗体和免疫组化等方面的科研试剂。这些用于免疫组化的体外诊断试剂（IVD）对于 BioLegend 公司目前的科研试剂产品线是一个很好的补充和扩展。科文斯抗体的客户将享有与 BioLegend 当前客户同样的优质服务和高性价比的产品。
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