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Santa Cruz  sc-255411    Penicillin G potassium salt

产品编号 sc-255411  |  santa cruz

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产品描述

Penicillin G potassium salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp. As an antibiotic, Penicillin G is noted to posses effectiveness mainly against gram-positive organisms. Some gram-negative organisms such as Neiserria gonorrhoeae and Neiserria meningitidis are also reported to be susceptible to Penicillin G. Penicillin G is also known as benzylpenicillin and contains a 6' phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose into penillic acid and penilloic acid. Penicillin G is also available as a non-salt (sc-344973) and in salt forms such as Penicillin G sodium (sc-257971).

参考文献

1. Schwartz, M.A. 1965. J Pharm Sci. 54: 472-473. PMID: 14301592
2. Demain, A.L. 1991. Proc. Natl. Sci. Counc. Repub. China B. 15: 251-265. PMID: 1815263
3. Livermore, D.M. 2009. Curr. Protein Pept. Sci. 10: 397-400. PMID: 19538149

外观 :

Powder

物理状态 :

Solid

溶解度 :

Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.

保存 :

Store at 4° C

熔点 :

214-217° C (lit.)

密度 :

1.36 g/cm3

折射率 :

n20D~1.66 (Predicted)

光学活性 :

α20/D 285º±15º, c = 1 in water

IC50 :

Penicillin-binding protein 1A: IC50= 0.002 µg/ml (Streptococcus pneumoniae serotype 4 ); Penicillin-binding protein 2B: IC50= 0.007 µg/ml (Streptococcus pneumoniae serotype 4 ); Penicillin-binding protein 2x: IC50= 0.007 µg/ml (Streptococcus pneumoniae serotype 4 ); Bacillus subtilis: IC50= 1.56 µg/ml; Staphylococcus aureus: IC50= 1.56 µg/ml

Ki 数据 :

Beta-lactamase TEM: Ki= 20 µM (Escherichia coli); Solute carrier family 22 member 8: Ki= 52.8 µM (rat); OAT3: Ki= 97.6 µM (human); Solute carrier family 22 member 6: Ki= 328 µM (mouse); Solute carrier family 22 member 6: Ki= 418 µM (rat)

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

德国水公害等级 :

2

RTECS :

XH9700000

PubChem CID :

23664709

默克索引 :

14: 7094

MDL 号码 :

MFCD00036193

EC号码 :

204-038-0

Beilstein 注册 :

3832841

SMILES :

CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[K+]

公司介绍

SANTA CRUZ公司是全球最大的抗体生产厂商之一，目前公司提供二万余种研究用的第一抗体，几乎覆盖了目前生命科学研究的各个最新领域，其每种抗体又有多个克隆可以选择，还提供一些对应蛋白标准品及相关产品，如ABC试剂盒，各种标记二抗，Western试剂盒，蛋白分子量Marker，核抽提物等，为免疫学研究工作提供了极大的方便。

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