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InvivoGen pnf3-lc1 pNiFty3-Lucia
pNiFty3-Lucia plasmid is composed of two key elements: the mouse interferon beta minimal promoter and a secreted luciferase (Lucias) reporter gene.
pNiFty3-SEAP plasmid is selectable with Zeocin™ in both E. coli and mammalian cells, and can be used to generate stable clones.
产品描述
pNiFty3
pNiFty3 plasmids are composed of an IFN-β proximal promoter, various transcription factor binding sites (TFBS) and a SEAP (secreted alkaline phosphatase) or secreted luciferase (Lucia) reporter gene.
pNiFty3 plasmids are selectable with Zeocin™ in both E. coli and mammalian cells, and can be used to generate stable clones.
pNiFty3-SEAP | Inducible SEAP reporter plasmid - mIFN-β promoter - ZeocinR | 20 µg |
pNiFty3-N-SEAP | Inducible SEAP reporter plasmid - mIFN-β promoter - NF-κB - ZeocinR | 20 µg |
pNiFty3-A-SEAP | Inducible SEAP reporter plasmid - mIFN-β promoter - AP-1 - ZeocinR | 20 µg |
pNiFty3-I-SEAP | Inducible SEAP reporter plasmid - mIFN-β promoter - ISRE - ZeocinR | 20 µg |
pNiFty3-T-SEAP | Inducible SEAP reporter plasmid - mIFN-β promoter - NFAT - ZeocinR | 20 µg |
pNiFty3-AN-SEAP | Inducible SEAP reporter plasmid - mIFN-β promoter - AP-1 NF-κB - ZeocinR | 20 µg |
pNiFty3-IAN-SEAP | Inducible SEAP reporter plasmid - mIFN-β promoter - ISRE AP-1 NF-κB - ZeocinR | 20 µg |
pNiFty3-TAN-SEAP | Inducible SEAP reporter plasmid - mIFN-β promoter - NFAT AP-1 NF-kB - ZeocinR | 20 µg |
pNiFty3-Lucia | Inducible Lucia luciferase reporter plasmid - mIFN-β promoter - ZeocinR | 20 µg |
pNiFty3-N-Lucia | Inducible Lucia luciferase reporter plasmid - mIFN-β promoter - NF-κB - ZeocinR | 20 µg |
pNiFty3-A-Lucia | Inducible Lucia luciferase reporter plasmid - mIFN-β promoter - AP-1 - ZeocinR | 20 µg |
pNiFty3-I-Lucia | Inducible Lucia luciferase reporter plasmid - mIFN-β promoter - ISRE - ZeocinR | 20 µg |
pNiFty3-T-Lucia | Inducible Lucia luciferase reporter plasmid - mIFN-β promoter - NFAT - ZeocinR | 20 µg |
pNiFty3-AN-Lucia | Inducible Lucia luciferase reporter plasmid - mIFN-β promoter - AP-1 NF-κB - ZeocinR | 20 µg |
pNiFty3-IAN-Lucia | Inducible Lucia luciferase reporter plasmid - mIFN-β promoter - ISRE AP-1 NF-κB - ZeocinR | 20 µg |
pNiFty3-TAN-Lucia | Inducible Lucia luciferase reporter plasmid - mIFN-β promoter - NFAT AP-1 NF-kB - ZeocinR | 20 µg |
其他产品线
1-Cell Culture and Transfection Reagents:
Powerful reagents to prevent microbial contamination in cell culture, plus a wide variety of selection antibiotics and reporter (secreted embryonic alkaline phosphatase (SEAP) or Lucia luciferase) detection reagents, and a transfection reagent;
2-Mammalian Expression Vectors:
A broad array of cloning vectors, that include plasmidic and lentiviral vectors, and CpG-free plasmids, a choice of inducible reporter plasmids, plus an expanding library of human and murine genes, and a wide variety of cellular promoters;
3-Reporter Cells:
A growing collection of functionally validated and mycoplasma-free human and murine cell lines, such as HEK293-, Jurkat-, RAW 264.7- and THP-1-derived cells, that report on one or more pattern recognition receptor (PRR), cytokine, or transcription factor activities using SEAP and/or Lucia luciferase, plus a recently launched line of knockout cells that lack major innate immune sensors or signaling proteins;
4-PRR Ligands:
An expanding collection of agonists and control ligands for all the major PRRs, such as Toll-like receptors (TLRs), NOD-like receptors (NLRs) and cytosolic DNA sensors (CDSs), including ligands of natural and synthetic origin, all screened and validated in-house;
5-Inhibitors:
A wide selection of functionally validated compounds to directly or indirectly block the principal immune (TLR, NLR, CDS) pathways and related signaling pathways;
6-Antibodies and Recombinant Proteins:
A large variety of biologically validated monoclonal and polyclonal antibodies against major human and murine innate immune targets, as well as isotype families of clinically relevant antibodies, plus a selection of recombinant cytokines;
7-Vaccination:
Pre-clinical grade vaccine adjuvants that comprise alum, emulsions, such as CFA and saponin, and PRR ligands, plus various ovalbumin-derived products.
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