Mesenchymal Stem Cell Medium Chemically Defined

Product Overview:

Stem cells possess the unique ability to proliferate as an undifferentiated cell type, then, when properly stimulated, differentiate into multiple lineages of cells. Lonza’s TheraPEAK™ MSCGM-CD™ Chemically Defined Mesenchymal Stem Cell Medium is a chemically defined, serum-free, xeno-free media designed to proliferate human bone marrow derived mesenchymal cells in an undifferentiated state. The medium has been specifically designed and tested to ensure that the medium neither promotes spontaneous differentiation of cells nor inhibits cell differentiation to osteogenic, chondrogenic, or adipogenic lineages (when properly stimulated with an appropriate differentiation media).

Serum-free media, such as  TheraPEAK™ MSCGM-CD™ Chemically Defined Mesenchymal Stem Cell Medium, are intended to support cell growth without serum supplementation. This medium is chemically defined indicating that it contain only constituents of known molecular structure. Lonza's TheraPEAK™ MSCGM-CD™ Chemically Defined Mesenchymal Stem Cell Medium is of primary interest to those seeking maximal control over research and manufacturing variables. TheraPEAK™ MSCGM-CD™ Chemically Defined Mesenchymal Stem Cell Medium's formulation is complete and contains human albumin, recombinant human insulin, pasteurized human transferrin, HEPES, and L-glutamine. TheraPEAK™ MSCGM-CD™ Chemically Defined Mesenchymal Stem Cell Medium does not contain phenol red or antibiotics.

Partial List of Cells Proliferated with TheraPEAK™ MSCGM-CD™ Chemically Defined Mesenchymal Stem Cell Medium*:

Human bone marrow derived stem cells

Human periodontal ligament derived stem cells

Human adipose derived stem cells

The figures below demonstrate the robust response exhibited by Poietics™ hMSC-Human Mesenchymal Stem Cells cultured in onza’s TheraPEAK™ MSCGM-CD™ Chemically Defined Mesenchymal Stem Cell Medium compared to DMEM plus 10% FBS. Cells were started the same day in uncoated flasks and photographed on the same day (100x).

The TheraPEAK™ MSCGM-CD™ Chemically Defined Mesenchymal Stem Cell Medium is offered as a BulletKit™ Medium (catalog no. 00190632) which includes both the basal media and the necessary supplements for proliferation of human bone marrow derived mesenchymal stem cells. The basal medium (MSCBM-CD Mesenchymal Basal Medium, Chemically defined; catalog no.00190620) and the necessary supplements (MSCGM-CD™ SingleQuots Kit ; catalog no. 00192125) can also be purchased individually.

Lonza guarantees the performance of Clonetics™/Poietics™ cells only if appropriate Clonetics™/Poietics™ media and reagents are used exclusively and the recommended storage and use protocols are followed. Any modifications made to the recommended cell systems including the use of alternative media, reagents or protocols, will void cell and media performance guarantees. If you need assistance in selecting the appropriate media, reagents, or protocol, please contact Lonza Scientific Support.

*List of cells generated from customer data. Lonza only routinely uses this medium with Lonza’s human bone marrow derived mesenchymal stem cells and can therefore only guarantee the successful use of this media with these cells.

Related products

Description                                                                        Catalog#                     Format    

MSCGM-CD™ BulletKit (00190620 and 00192125)             190632       KT

MSCBM-CD Mesenchymal Basal Medium, Chemically defined, 500 ml    190620    BOT

MSCGM-CD SingleQuots Kit       192125        KT

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